Tinospora cordifolia (Giloy) - Therapeutic Uses and Importance: A review

  • Charu Saxena Department of Pharmaceutics, Kharvel Subharti College of Pharmacy, Swami Vivekanand Subharti University, Meerut (U.P.)-250005
  • Geeta Rawat Department of Pharmacology, Kharvel Subharti College of Pharmacy, Swami Vivekanand Subharti University, Meerut (U.P.)-250005


Natural products having medicinal value are gaining more importance in clinical research now days due to their better pharmacological response and no side effects as compared to allopathic drugs. Tinospora cordifolia common name is “Guduchi” or “Giloy” is known for its application in the treatment of various diseases in the traditional ayurvedic literature. Active components obtained from the plant and their biological function in disease control has led to active interest in the plant. This review contains venicular name of plant, various components, their uses in targeting diseases .Giloy is an very important plant for treatment of various diseases.

Keywords: Ayurveda, giloy, diseases, natural product, plant, tinospora


1. Rana V, Thakur K, Sood R, Sharma V, Sharma TR. Genetic diversity analysis of Tinospora cordifoliagermplasm collected from northwestern Himalayan region of India. J Genet. 2012; 91:99–103.
2. Parthipan M, Aravindhan V, Rajendran A. Medico-botanical study of Yercaud hills in the eastern Ghats of Tamil Nadu, India. Anc Sci Life. 2011; 30:104–9.
3. The Ayurvedic Pharmacopoeia of India. Part I. 1st ed. Vol. 1. New Delhi: Department Of AYUSH, Ministry of Health and FW; 2001. pp. 53–5.
4. Upadhyay AK, Kumar K, Kumar A, Mishra HS. Tinospora cordifolia (Willd.) Hook. f. and Thoms. (Guduchi)-validation of the Ayurvedic pharmacology through experimental and clinical studies. Int J Ayurveda Res. 2010; 1:112–21.
5. Sharma U, Bala M, Kumar N, Singh B, Munshi RK, Bhalerao S. Immunomodulatory active compounds from Tinospora cordifolia. J Ethnopharmacol. 2012;141:918–26
6. Sharmapriyavrat,Chaukambha Vishvbharti ,Ed-I,Re 2001,Page 75.
7. Patel SS, Shah RS, Goyal RK. Antihyperglycemic, antihyperlipidemic and antioxidant effects of Dihar, a polyherbal ayurvedic formulation in streptozotocin induced diabetic rats. Indian J Exp Biol. 2009; 47: 564–70.
8. Gupta R, Sharma V. Ameliorative effects of Tinospora cordifolia root extract on histopathological and biochemical changes induced by aflatoxin-b (1) in mice kidney. Toxicol Int. 2011; 18: 94–8.
9. Jagetia GC, Rao SK. Evaluation of the antineoplastic activity of guduchi (Tinospora cordifolia) in ehrlich ascites carcinoma bearing mice. Biol Pharm Bull. 2006; 29: 460–6.
10. Patel MB, Mishra S. Hypoglycemic activity of alkaloidal fraction of Tinospora cordifolia. Phytomedicine. 2011; 18:1045–52.
11. Ly PT, Singh S, Shaw CA. Novel environmental toxins: Steryl glycosides as a potential etiological factor for age-related neurodegenerative diseases. J Neurosci Res. 2007; 85:231–7.
12. Karpova EA, Voznyi Ya V, Dudukina TV, Tsvetkova IV. 4-Trifluoromethylumbelliferyl glycosides as new substrates for revealing diseases connected with hereditary deficiency of lysosome glycosidases. Biochem Int. 1991; 24:1135–44.
13. Kapil A, Sharma S. Immunopotentiating compounds from Tinospora cordifolia. J Ethnopharmacol. 1997; 58:89–95.
14. Chen S, Wu K, Knox R. Structure-function studies of DT-diaphorase (NQO1) and NRH: Quinone oxidoreductase (NQO2) Free Radic Biol Med. 2000; 29: 276–84.
15. Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. J Clin Invest. 2001; 107: 241–6.
843 Views | 747 Downloads
How to Cite
Charu Saxena, and Geeta Rawat. “Tinospora Cordifolia (Giloy) - Therapeutic Uses and Importance: A Review”. Current Research in Pharmaceutical Sciences, Vol. 9, no. 3, Oct. 2019, doi:10.24092/CRPS.2019.090302.
Review Articles