Current Research in Pharmaceutical Sciences

TRANSFORMING PHARMACY EDUCATION IN INDIA: A CRITICAL REVIEW OF THE NEW B.PHARM CURRICULUM (2026) UNDER THE NATIONAL EDUCATION POLICY 2020

Hemant Kumar Sharma — Mon, 21 Sep 2026 11:07:59 +0530

The Bachelor of Pharmacy (B.Pharm) programme in India is undergoing a major curricular transformation with the introduction of the revised Pharmacy Council of India (PCI) curriculum aligned with the National Education Policy (NEP) 2020. The revised curriculum is intended for implementation from the academic session 2026–27 and introduces a broader competency-oriented approach to pharmacy education. This review critically examines the structure, emerging domains, educational philosophy, opportunities, and implementation challenges associated with the revised curriculum. Particular attention is given to the integration of Python programming, pharmaceutical data analytics, machine learning, artificial intelligence, healthcare psychology, communication skills, innovation and entrepreneurship, pharmacovigilance, regulatory affairs, research methodology, internships, and contemporary pharmaceutical technologies. The curriculum represents a transition from predominantly discipline-centered learning towards a more interdisciplinary, technology-enabled, experiential, and competency-oriented model. Such a transition is consistent with international developments in competency-based pharmacy education and the increasing digitalization of healthcare. However, effective implementation will require faculty development, infrastructure strengthening, curriculum mapping, appropriate assessment strategies, industry and hospital partnerships, and institutional quality assurance. The revised curriculum provides a strong foundation for preparing future pharmacists for pharmaceutical industry, clinical practice, research, regulatory science, public health, and digital healthcare. Continuous monitoring and outcome-based evaluation will be essential to determine whether the intended curricular reforms translate into measurable improvements in graduate competence and employability.

ASSESSMENT OF ANTI-INFLAMMATORY ACTION OF VITEXIN USING IN VITRO MODELS

Abhishek Kashyap, Faizan Ali — Mon, 21 Sep 2026 11:10:32 +0530

In the present work the in vitro anti-inflammatory potential of vitexin was evaluated using two different models of inflammation, viz., inhibition of protein denaturation and inhibition of protease action. Both these models are based on the chemical mediators of inflammation and evaluating the drug on these models is self-evident of its anti-inflammatory property. Vitexin is a natural flavanol glycoside with iron chelating and antioxidant properties. It has diverse actions at the cellular and physiological levels, demonstrating anti-inflammatory, anti-cancer, and anti-fibrosis effects in animal models. The presence of peaks at 1727, 3407, 1462 and 2842 are indicative of the presence of carbonyl, hydroxyl, aromatic ring and aliphatic carbon respectively. The results of solubility analysis indicate that vitexin is soluble in organic solvents easily and is partially or sparingly soluble in aqueous solutions. The capacity of different concentrations of vitexin to inhibit protein denaturation of albumin was ranging from 20.33 ± 0.129 % to 69.63 ± 0.213 % in the assay and hence provides yet another evidence for its excellent anti-inflammatory property. The capacity of different concentrations of vitexin to inhibit serine protease was found to be ranging from 18.12 ± 0.214% to 75.21 ± 0.315% in the assay and therefore reinforces its tremendous anti-inflammatory property.

SUSTAINABLE SYNTHESIS, STRUCTURAL CHARACTERIZATION, AND ANTIMICROBIAL PROFILING OF 1,3,5-TRIAZINE DERIVATIVES VIA ULTRASOUND APPROACH

Srinkhla Kumari, Ankit Diwan, Trapti Shrivastava, Kuldeep Ganju — Mon, 21 Sep 2026 11:12:31 +0530

The present study describes the sustainable synthesis, structural characterization, and antimicrobial evaluation of trisubstituted 1,3,5-triazine derivatives using an ultrasound-assisted approach. A three-step synthetic pathway involving successive nucleophilic substitution of cyanuric chloride was employed to obtain five derivatives (TSa-e). The compounds were characterized by FTIR, 1H-NMR, and mass spectrometry, confirming the incorporation of functional groups and substitution patterns. Physicochemical properties, including solubility, melting point, and retention factor were determined. Antibacterial activity was assessed against Escherichia coli (MTCC 40) and Staphylococcus aureus (MTCC 3160) using disc diffusion and broth dilution methods. Among the synthesized derivatives, TSc (N2,N4,N6-triphenyl-1,3,5-triazine-2,4,6-triamine) exhibited the most potent activity with IC50 values of 52.15 µg/mL (E. coli) and 76.13 µg/mL (S. aureus), suggesting enhanced lipophilicity improved antibacterial efficacy. Electron-withdrawing substituents (Cl, Br) reduced activity compared to unsubstituted or alkyl-substituted derivatives. The study highlights ultrasound-assisted synthesis as a green and efficient method for preparing bioactive triazine derivatives with promising antibacterial potential.